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Forum » MultyLanguage FORUM » Русский чат (Russian) » Русский чат (Russian)
Русский чат (Russian)
BULL_EGGSДата: Saturday, 2015-12-12, 11:19 PM | Сообщение # 1
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shmelovsergeyДата: Sunday, 2015-12-13, 1:51 AM | Сообщение # 2
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smok Проба пера
BULL_EGGSДата: Sunday, 2015-12-13, 3:45 PM | Сообщение # 3
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Bomm Bom)
ARMAVIRДата: Sunday, 2015-12-13, 3:46 PM | Сообщение # 4
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Ну вот, все заработало =) biggrin
shmelovsergeyДата: Sunday, 2015-12-13, 4:46 PM | Сообщение # 5
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Quote ARMAVIR ()
Ну вот, все заработало =)
arinnn111Дата: Monday, 2016-01-04, 0:08 AM | Сообщение # 6
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что с сервером пехота?
BULL_EGGSДата: Monday, 2016-01-04, 4:03 AM | Сообщение # 7
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Не знаю. Фортим молчит пока. Заявку еще днем отправил, что сервер недоступен.
fmyykjhДата: Saturday, 2016-10-08, 1:02 PM | Сообщение # 8

Varenicline (employment name Chantix in the USA and Champix in Canada, Europe and other countries, marketed close to Pfizer, generally speaking in the practice of varenicline tartrate), is a prescription medication habituated to to deal with nicotine addiction. Varenicline is a nicotinic receptor partial agonist—it stimulates nicotine receptors more weakly than nicotine itself does. In this admiration it is similar tocytisine and conflicting from the nicotinic enemy, bupropion, and nicotine replacement therapies (NRTs) like nicotine patchesand nicotine gum. As a fragmentary agonist it both reduces cravings looking for and decreases the pleasurable effects of cigarettes and other tobacco products. By virtue of these mechanisms it can help some patients to discharged smoking.
Medical uses
Varenicline is indicated representing smoking cessation. In a 2006 randomized controlled hearing sponsored through Pfizer, after only year the figure of persistent abstinence was 10% in place of placebo, 15% for bupropion and 23% to go to varenicline.<>] In a 2009 meta-analysis of 101 studies funded via Pfizer, varenicline was establish to be more powerful than bupropion (odds correlation 1.40) and NRTs (odds correlation 1.56).<>]
A Cochrane businesslike scrutinize concluded that varenicline improved the distinct possibility of successfully quitting smoking sooner than two- to three-fold corresponding to to pharmacologically unassisted attempts. Varenicline was more efficacious than bupropion in this view but not statistically superior to NRT.<>]
The FDA has approved the ingest of varenicline representing up to twelve weeks. If smoking cessation has been achieved it may be continued as a service to another twelve weeks.<>]
Varenicline has not been tested in those below 18 years close or pregnant women and so is not recommended in behalf of profit by alongside these groups.
Adverse effects
Nausea occurs commonly in people winning varenicline. Other less common side effects classify headache, gordian knot embarrassment sleeping, and irregular dreams. Rare side effects reported via people entrancing varenicline compared to placebo categorize difference in taste, vomiting,abdominal tribulation, flatulence, and constipation. In a recent meta-analysis ownership papers past Leung et al., it has been estimated that for every five subjects bewitching varenicline at sustentation doses (1 mg twice routine), there will be an experience of nausea, and in spite of every 24 and 35 treated subjects, there will be an anyway in the reality of constipation and flatulence respectively. Gastrointestinal side-effects are superior factors compromising the compliance of varenicline.<>]<>]
Despair and suicide
In November 2007, the FDA announced it had received post-marketing reports that patients using varenicline for smoking cessation had knowing very many pensive side-effects, including suicidal ideation and additional suicidal behavior, haphazard behavior, and drowsiness. On February 1, 2008 the FDA issued an wide awake to in addition make plain its findings, noting that "it appears increasingly likely that there is an association between Chantix and serious neuropsychiatric symptoms". It is unexplored whether the psychiatric symptoms are mutual to the cure or to nicotine withdrawal symptoms,<citation>needed] although not all patients had stopped smoking. The FDA also recommended that condition vigilance professionals and patients ready for for the benefit of behavioral and spirit changes.<>] In May 2008, Pfizer updated the shelter communication associated with varenicline, noting that "some patients have reported changes in behavior, agitation, depressed well-disposed, suicidal thoughts or actions."<>]
As of July 1, 2009, the US Food and Hypnotic Provision requires Chantix (varenicline) to effect a swart package trap notice, the medium's strongest safeness caution, justified to public reports of side effects including despair, suicidal thoughts, and suicidal actions.<>]
From <a href=http://www.fmyykj.com>suzhou pharmaceutical technology co.,ltd.</a>
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